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PENTACLETHRAMIDOPROPYL DIMETHYLAMINE.

Insufficient Data CAS 2180952-74-1 / HAIR CONDITIONING

Pentaclethramidopropyl Dimethylamine is primarily recognized as an advanced hair conditioning agent that significantly enhances hair fiber integrity and appearance. While its efficacy is well-documented within hair care formulations, there is currently no specific data available regarding its direct application or effects on skin.

Summary

hair conditioning surfactant

Science

Mechanism of Action

This compound primarily functions on hair by leveraging its 'amidopropyl dimethylamine' structure to interact with the hair fiber's negatively charged surface. This interaction helps to restore structural integrity, promote fiber alignment, and enhance overall strength, leading to decreased porosity and improved volume control. These actions collectively contribute to increased glossiness, manageability, shine, and better combability by effectively sealing the hair cuticles.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 When included at 1.50% as a component of the Capillus Pro 22 blend (which also contains Glycerin), clinical observations indicate its ability to restore, align, and strengthen hair fibers. This leads to quantifiable improvements such as reduced hair porosity, enhanced volume control, increased glossiness and shine, better manageability, sealed cuticles, and improved hair combability.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH 4 – 4.5
0 7 14

Stability

Formulations containing Pentaclethramidopropyl Dimethylamine, particularly when part of the Capillus Pro 22 blend, typically demonstrate optimal stability and performance within a narrow acidic pH range of 4.0 to 4.5.

Synergies

  • Glycerin (as part of Capillus Pro 22 blend)

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk Unknown

The Scientific Committee on Consumer Safety (SCCS) of the EU Commission has evaluated this substance, noting its approval for cosmetic use subject to specific restrictions outlined in Annex III of the EC Cosmetics Regulation. These restrictions may pertain to purity criteria, maximum concentration levels, or specific product categories. While a direct SCCS opinion detailing explicit restrictions for Pentaclethramidopropyl Dimethylamine itself was not located, related 'Fatty Acid Amidopropyl Dimethylamines' have been deemed safe by the CIR Expert Panel, contingent upon maintaining sensitizing impurities, such as 3,3-dimethylaminopropylamine (DMAPA) and amidoamine, at levels that do not induce sensitization.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

Primarily a hair conditioning agent with documented benefits for hair fiber integrity and appearance; however, there is insufficient specific data regarding its efficacy or safety for direct skin applications within a precision skincare context.

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