Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
No information suggests that PEI-45 is commonly 'dusted' or used deceptively. Its established utility and applications in skincare formulations are not evident from the available data.
The Formula
Formulation
Stability
Specific stability data for PEI-45 within cosmetic formulations is not available. For general polyethylenimine (PEI) in research contexts, it is noted to be water-soluble and stable around pH 7.0-7.5. Its protonation state, which can affect polyplex formation and stability, is observed to change with varying pH values, such as pH 6.0.
Safety
Safety Profile
PEI-45 has not undergone specific safety assessment by the Cosmetic Ingredient Review (CIR), Scientific Committee on Consumer Safety (SCCS), or the FDA as a skincare ingredient. While Polyethylenimine (PEI) is a subject in other scientific fields (e.g., biomedical research), there is no readily available data concerning the safety profile, potential dermal irritation, or sensitization specifically for PEI-45 in topical cosmetic applications.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Due to a substantial lack of specific research, clinical studies, and formal regulatory assessments as a skincare ingredient, the efficacy, safety, and optimal application of PEI-45 cannot be reliably determined at this time.
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References
Sources