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Moumoujus

PEI-10.

Valuable CAS 9002-98-6 / VISCOSITY CONTROLLING

PEI-10 is a polycationic polymer widely utilized in precision skincare formulations for its film-forming and conditioning properties, which enhance skin smoothness and support moisture retention. It also effectively functions as a viscosity controlling agent, contributing to product texture and stability across various applications.

Summary

viscosity controlling film-forming conditioning

Science

Mechanism of Action

As a cationic polymer featuring primary, secondary, and tertiary amino groups, PEI-10 exhibits a polycationic character that drives its high adhesion and adsorption to skin. These amino groups interact with skin proteins and other functional groups, forming a protective film. This action results in enhanced skin conditioning and moisture retention. Its inherent cationicity further allows for the neutralization and adsorption of anionic substances, alongside the chelation of heavy metal ions.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Polyethylenimine solutions generally exhibit robust pH buffering capacity and can maintain stability across a wide pH range. While a 5% aqueous solution typically shows a pH of 10–12, formulations are reported stable at more neutral pH values, such as 6.9-7.5. Linear PEI specifically dissolves in hot water and at lower pH levels, whereas the protonation of amines in branched PEIs is pH-dependent.

Conflicts

  • strong acids
  • oxidizing agents
  • other chemicals it can react vigorously with

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

EWG Skin Deep assesses PEI-10 with 'LOW' concern across categories including cancer, allergies & immunotoxicity, developmental and reproductive toxicity. However, Environment Canada has classified general polyethylenimine as potentially toxic or harmful to the environment. While direct contact with general PEI can lead to severe irritation of skin and eyes, PEI-10 is noted as a preferred option for sensitive skin formulations, providing mild benefits without irritation. It also has FDA approval for certain biomedical applications, and potential toxicity concerns can be mitigated through conjugation with other polymers.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Medium
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

PEI-10 is a valuable multi-functional polymer that significantly enhances skin conditioning, moisture retention, and product stability across a range of skincare formulations, especially beneficial for dry and sensitive skin types.

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