Science
Mechanism of Action
This ingredient acts as a skin conditioning agent, providing exogenous lipids to fortify the skin barrier, thereby improving hydration and offering protection against inflammation. As a surfactant, it lowers surface tension to facilitate the formation of stable oil-in-water emulsions and enables efficient removal of dirt and impurities during cleansing. Additionally, it functions as a solvent and solubilizer for active ingredients, fragrance oils, and colorants, and can significantly enhance the dermal penetration of other substances within topical formulations.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Polyethylene glycols (PEGs) are prone to aging, which can lead to alterations in their chemical properties, specifically a reduction in pH and an increase in ionic strength. For optimal stability, PEG solutions are best stored frozen at -20°C or refrigerated at 4°C, as room temperature storage is less stable. Minimizing exposure to oxygen and light during storage can also mitigate aging effects.
Conflicts
- Its ability to enhance the penetration of other ingredients through the skin necessitates careful formulation, especially when combined with compounds whose safety is contingent on limited dermal absorption.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel concluded that PEGylated alkyl glycerides, including PEG-70 Mango Glycerides, are safe under current practices of use and concentration, provided they are formulated to be non-irritating. This determination supersedes previous concentration limits. The U.S. Food and Drug Administration (FDA) has also recognized related PEGylated alkyl glycerides as safe for specific, limited food uses. However, concerns persist regarding potential impurities like ethylene oxide and 1,4-dioxane, classified as carcinogens, which may arise during the ethoxylation process; thus, the ultimate safety relies on the purity of the final product.
Your Skin
Skin Compatibility
Our Assessment
Verdict
PEG-70 Mango Glycerides is a valuable multi-functional ingredient due to its emollient, cleansing, solubilizing, and penetration-enhancing properties, generally considered safe as used, although rigorous control over product purity and careful formulation are critical.
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