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PEG-5 GLYCERYL TRIOLEATE.

Valuable CAS 68958-64-5 / SKIN CONDITIONING - EMOLLIENT, SURFACTANT - EMULSIFYING

PEG-5 Glyceryl Trioleate is a versatile PEGylated ester known for its dual functionality as an emollient and emulsifier. It enhances skin hydration while crucially aiding in the creation of stable oil-in-water formulations in skincare products.

Summary

Emollient Emulsifier Skin Conditioning Agent Surfactant Cleansing Agent

Science

Mechanism of Action

As an emollient, PEG-5 Glyceryl Trioleate contributes to moisture retention by establishing hydrogen bonds with water molecules, thereby diminishing transepidermal water loss and benefiting dry skin. In its role as an emulsifier, it facilitates the uniform dispersion of oil and water phases, ensuring product stability and desirable texture by reducing interfacial tension.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

PEG-5 Glyceryl Trioleate maintains stability but is susceptible to oxidation. It is also prone to hydrolysis under exposure to strong acidic or strong alkaline conditions, suggesting an optimal pH range around neutral to mildly acidic or alkaline environments.

Conflicts

  • strong oxidizing agents
  • strong acids
  • strong alkalis

Safety

Safety Profile

CIR Status
Safe as used
Sensitization risk Low

The CIR Expert Panel concluded that PEGylated alkyl glycerides, including PEG-5 Glyceryl Trioleate, are safe for use under current practices and concentrations, provided formulations are non-irritating. While a specific maximum concentration for PEG-5 Glyceryl Trioleate is not defined, a related class, PEG glyceryl cocoates, was found safe in leave-on products up to 10%. PEGs generally demonstrate low systemic toxicity on intact skin. However, sensitization and nephrotoxicity have been observed in burn patients treated with PEG-based creams, indicating that PEGylated ingredients should not be applied to damaged skin. It is imperative that manufacturers remove potential impurities like 1,4-dioxane (a possible carcinogen) and unreacted ethylene oxide residues through appropriate purification procedures.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

PEG-5 Glyceryl Trioleate is a valuable ingredient for its essential emulsifying and emollient capabilities, contributing to product stability and skin hydration, provided it is formulated to be non-irritating and free of impurities.

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