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PEG-45 SAFFLOWER GLYCERIDES.

Valuable / SURFACTANT - EMULSIFYING

PEG-45 Safflower Glycerides is a derivative of safflower oil, chemically modified with an average of 45 moles of ethylene oxide. This versatile ingredient functions primarily as both a skin conditioning agent and a crucial surfactant in formulations.

Summary

Emollient Emulsifier Surfactant Skin Conditioning Agent Solubilizer Lubricant Dispersant

Science

Mechanism of Action

On the skin, it contributes to conditioning. In cosmetic formulations, its surfactant properties are paramount; it effectively emulsifies immiscible oil and water phases to create stable products. Additionally, it acts as a solubilizer for hydrophobic compounds in aqueous systems, a lubricant for improved application, and a dispersant, ensuring uniform distribution of ingredients for optimal product performance.

Research

Clinical Evidence

Insufficient-data confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Safe with restrictions
Max tested
10%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has concluded that PEG-45 Safflower Glycerides is safe for cosmetic use when formulated to be non-irritating. A maximum concentration of 10% is recommended for leave-on products, with higher concentrations permissible in rinse-off formulations. While undiluted forms of related PEGylated glycerides have shown irritation, clinical data for similar ingredients at 2% indicated non-to-mild irritation. The base mono- and diglycerides are generally recognized as safe by the FDA.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

PEG-45 Safflower Glycerides is a valuable multi-functional ingredient, acting as an emulsifier, solubilizer, and skin conditioning agent, enhancing formulation stability and ingredient delivery across all skin types.

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