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PEG-4 METHYL ETHER.

Valuable CAS 9004-74-4 / HUMECTANT, SOLVENT

PEG-4 Methyl Ether is a versatile synthetic ingredient functioning as an emollient, humectant, and solvent. It significantly enhances skin hydration, improves product texture, and facilitates the penetration of other active ingredients into the skin.

Summary

humectant solvent emollient viscosity controller

Science

Mechanism of Action

This ingredient operates as a humectant by forming hydrogen bonds with water molecules, thereby attracting and retaining moisture, which minimizes transepidermal water loss and provides sustained hydration. As a solvent, it aids in dissolving other components within a formulation, improving their distribution and efficacy. Its emollient properties soften and soothe the skin, while its ability to control viscosity contributes to an improved product feel and spreadability.

Research

Clinical Evidence

Medium confidence
Effective range ≤20%
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The provided research data does not indicate that PEG-4 Methyl Ether is commonly associated with 'dusting' issues in formulations.

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

PEG-4 Methyl Ether maintains a neutral pH and exhibits general stability under normal conditions. However, as an ether, it can form potentially explosive peroxides when exposed to air or oxygen during storage, a process accelerated by light, metal catalysts, and aldehydes. Distillation to dryness should be avoided to prevent peroxide concentration.

Conflicts

  • Phenol
  • Cresol
  • Resorcinol
  • Tannin
  • Air/Oxygen (during storage, risk of peroxide formation)
  • Light (accelerates peroxide formation)
  • Metal catalysts (accelerates peroxide formation)
  • Aldehydes (accelerates peroxide formation)

Safety

Safety Profile

CIR Status
Safe as used
Max tested
20%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel deems PEG-4 Methyl Ether safe for cosmetic use, noting its low toxicity and minimal risk of irritation or sensitization on intact skin. Significant skin penetration occurs primarily when the skin barrier is severely compromised, such as in cases of second or third-degree burns. A patch test is advisable for individuals with exceptionally sensitive skin. It is recognized by the EPA Safer Choice program as an ingredient of low concern.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

PEG-4 Methyl Ether is a valuable, well-tolerated ingredient that enhances hydration, improves formula aesthetics, and supports the delivery of other actives across all skin types.

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