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PEG-33 CASTOR OIL.

Valuable CAS 61791-12-6 / SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

PEG-33 Castor Oil is a polyethylene glycol derivative of castor oil, primarily functioning as a non-ionic surfactant, emulsifier, and solubilizing agent. It facilitates the stable mixing of oil and water phases, allowing other ingredients to dissolve effectively in cosmetic formulations.

Summary

Emulsifying Solubilizer Surfactant Cleansing Agent

Science

Mechanism of Action

This ingredient operates by lowering the surface tension between immiscible liquids, such as oil and water, thereby forming stable emulsions. As an emulsifier and solubilizer, it enhances the dissolution of hydrophobic compounds into aqueous solutions. While direct skin mechanisms for PEG-33 Castor Oil are less documented, related PEGylated castor oils have demonstrated potential to improve skin barrier function, offer moisturizing benefits, support stratum corneum repair, and exhibit anti-inflammatory effects by inhibiting mediator release.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Generally negative for irritation and sensitization, but irritation observed on intact skin at 50% for PEG-35 Castor Oil.
  2. 02 Used in a skin irritation study in guinea pigs.

Transparency

Dusting Analysis

Not commonly dusted

No data regarding dusting behavior is available for PEG-33 Castor Oil.

The Formula

Formulation

Solubility
Both
Optimal pH 5.5 – 7
0 7 14

Stability

Similar PEGylated castor oils, like PEG-40 Hydrogenated Castor Oil, are recognized for their robust resistance to oxidation and chemical degradation, contributing to enhanced product stability and longevity. Being non-ionic, PEG-33 Castor Oil is expected to maintain its activity across a broad pH spectrum, from acidic to alkaline conditions, making it versatile for various formulations.

Safety

Safety Profile

CIR Status
Safe as used
Max tested
50%
Sensitization risk Moderate

The CIR Expert Panel deems PEG-33 Castor Oil safe for cosmetic use up to 50% concentration. While generally not irritating or sensitizing on its own, studies indicate that high concentrations (50% PEG-35 Castor Oil) can cause irritation on intact skin and may increase the sensitization potential of other co-formulated ingredients. Minor amounts of 1,4-dioxane, a processing byproduct, can be present but are controlled through purification processes. It also holds FDA approval for indirect food contact applications.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

PEG-33 Castor Oil is a valuable cosmetic ingredient, primarily acting as an emulsifier and solubilizer to improve product texture and stability, with a generally low irritancy profile when used within established safety limits.

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