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Moumoujus

PEG-3 COCAMINE.

Insufficient Data CAS 61791-14-8 / SURFACTANT - EMULSIFYING

PEG-3 Cocamine is a multi-functional ethoxylated fatty amine primarily acting as a surfactant. Its role involves decreasing surface tension to stabilize emulsions and enhance the solubility of other formulation components, functioning as an emulsifying, solubilizing, and cleansing agent.

Summary

Surfactant/Cleansing Emulsifying Solubilizing

Science

Mechanism of Action

Operating as a surfactant, PEG-3 Cocamine facilitates the creation of stable emulsions by reducing the interfacial tension between immiscible phases. This mechanism also improves the dissolution of various ingredients within a solvent system, thereby contributing to the product's consistency, spreadability, and efficacy in cleansing.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

This ingredient can be formulated to maintain a low moisture content, typically not exceeding 1%. It exhibits very low vapor pressure at standard ambient temperatures, indicating good physical stability within products.

Conflicts

  • Formulation must rigorously control levels to ensure the final product is non-irritating, particularly when intended for use on compromised or sensitive skin.
  • Strict purification is paramount to minimize the presence of 1,4-dioxane and ethylene oxide, which are potential ethoxylation by-products.
  • Combining PEG-3 Cocamine with primary or secondary amines should be avoided to mitigate the risk of nitrosamine formation.

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) Expert Panel has consistently determined that safety data for PEG-3 Cocamine remains insufficient, both in their 1999 and 2015 assessments. Key data gaps include genotoxicity in a mammalian system, 28-day dermal toxicity, and dermal sensitization studies. Significant concerns pertain to potential impurities such as 1,4-dioxane and ethylene oxide, which necessitate stringent purification. The ingredient also carries a risk of nitrosamine formation if primary or secondary amines are present in the formulation. While specific data for PEG-3 Cocamine is limited, related PEG Cocamine compounds have been associated with mild to moderate skin and ocular irritation.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

Given the CIR Expert Panel's designation of insufficient safety data and the documented risks of impurities and potential irritation, PEG-3 Cocamine is not recommended for use in precision skincare formulations without comprehensive additional research and stringent quality control.

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