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PEG-25 GLYCERYL OLEATE.

Valuable CAS - / SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

PEG-25 Glyceryl Oleate is a versatile polyoxyethylenated ester of glycerin and oleic acid, primarily functioning as a surfactant and skin conditioning agent. It aids in effective cleansing by emulsifying oils and dirt, while simultaneously enhancing skin hydration and barrier function through its emollient and humectant properties.

Summary

Cleansing Agent Emulsifier Solubilizer Humectant Emollient Solvent

Science

Mechanism of Action

This ingredient operates through several key mechanisms on the skin. As a surfactant, it acts as a solubilizer and emulsifier, enabling the dispersion of oil-soluble ingredients in water and facilitating the gentle removal of sebum and impurities. For skin conditioning, it forms a protective layer to improve smoothness and moisture retention, contributing to the restoration of the skin's lipid barrier by mimicking natural skin lipids. The polyethylene glycol (PEG) component specifically draws and binds water molecules, providing sustained hydration and reducing transepidermal water loss.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

While no specific optimal pH range is defined for PEG-25 Glyceryl Oleate, related PEG esters such as PEG-25 Stearate exhibit stability across heat, acids, and bases, with a 1% aqueous solution maintaining a pH of 5.0-7.5. Non-PEG Glyceryl Oleate typically functions optimally within a pH range of 3-7.

Conflicts

  • Use on damaged or compromised skin is contraindicated due to historical evidence of sensitization and nephrotoxicity with PEG-based ingredients in burn patients, a specific caveat that persists for PEG Propylene Glycol Oleates.
  • Requires stringent purification to control potential impurities including ethylene oxide (maximum 1 ppm), 1,4-dioxane (maximum 5 ppm), polycyclic aromatic compounds (maximum 1 ppm), and heavy metals (maximum 10 ppm combined).
  • Risk of cross-sensitization exists with other PEG derivatives (e.g., PEG ethers, PEG fatty acid esters) due to shared structural characteristics.

Safety

Safety Profile

CIR Status
Safe with restrictions
Max tested
10%
Sensitization risk Moderate

The Cosmetic Ingredient Review (CIR) Expert Panel deemed related PEG Propylene Glycol Esters, including PEG-25 Glyceryl Oleate, safe for cosmetic use at concentrations up to 10% when formulated to be non-irritating. A critical restriction remains: this ingredient should not be applied to damaged or severely compromised skin to mitigate sensitization and systemic toxicity risks. Strict control of impurities (e.g., ethylene oxide, 1,4-dioxane) is also essential for safe formulation.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

PEG-25 Glyceryl Oleate is a valuable multi-functional ingredient, effectively cleansing and conditioning the skin, but requires meticulous formulation to control impurities and must be strictly avoided on damaged skin.

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