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PEG-25 GLYCERYL ISOSTEARATE.

Valuable / SURFACTANT - EMULSIFYING

PEG-25 Glyceryl Isostearate is a versatile ingredient functioning primarily as an emulsifier and surfactant, enabling the stable blending of oil and water in skincare formulations. It also acts as a humectant, drawing moisture to the skin, and contributes to overall skin conditioning.

Summary

Surfactant Emulsifier Humectant Skin Conditioner Viscosity Modifier Penetration Enhancer

Science

Mechanism of Action

This compound primarily operates by reducing the surface tension between immiscible phases, thus acting as a surfactant and emulsifier to create stable emulsions. As a humectant, it attracts and retains water in the stratum corneum, supporting skin hydration. Furthermore, consistent with other polyethylene glycols (PEGs), it may enhance the dermal penetration of other active ingredients present in a formulation.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 5 – 7.5
0 7 14

Stability

Based on a related compound, PEG-25 Stearate, this ingredient is expected to exhibit low vapor pressure and maintain stability across various temperatures, acidic, and basic conditions. The optimal pH range for a 1% aqueous solution is typically between 5.0 and 7.5.

Synergies

  • May enhance the penetration of other active ingredients into the skin.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

While PEG-25 Glyceryl Isostearate has not been individually reviewed by the Cosmetic Ingredient Review (CIR) Expert Panel, broader categories such as PEG Stearates (which include PEG-25 Stearate) have been deemed safe under current cosmetic use concentrations. Clinical data on several PEG Stearates (PEG-2, -8, -40, -50, and -100 Stearates) indicates they are neither irritants nor sensitizers at concentrations up to 25 percent. A similar, but distinct, ingredient, PEG-25 Propylene Glycol Stearate, was considered safe at concentrations not exceeding 10% in cosmetic formulations and classified as nonallergenic in various tests. Concerns exist regarding potential contamination with 1,4-dioxane and ethylene oxide, byproducts of the ethoxylation process, which formulators are expected to control through purification.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

PEG-25 Glyceryl Isostearate is a valuable multi-functional ingredient for formulation stability and skin conditioning, though its specific safety has not been individually reviewed by the CIR, with broader PEG categories showing a low risk of irritation.

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