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PEG-240.

Valuable CAS 25322-68-3 / HUMECTANT, SOLVENT

PEG-240 is a high molecular weight polyethylene glycol primarily functioning as a humectant, delivering gradual and long-term hydration to the skin by attracting and retaining water molecules. It also acts as a texture enhancer and stabilizer in formulations, deemed safe for use across all skin types.

Humectant Texture Enhancer Emulsifying Viscosity Increasing Agent/Stabilizer

Science

PEG-240 operates by forming hydrogen bonds with water molecules, effectively drawing and retaining moisture within the skin for prolonged hydration. Its barrier-forming properties additionally help to minimize transepidermal water loss, supporting the restoration of the skin's natural barrier function, particularly beneficial for dry conditions. As a solid PEG, it also contributes to the desired consistency of cosmetic formulations.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Polyethylene glycols demonstrate general stability. As the molar mass increases, there is a corresponding decrease in water solubility and hygroscopicity. Solid PEGs, such as PEG-240, are additionally utilized as consistency enhancers in formulations.


Safety

CIR Status
Safe as used
Sensitization risk Low

The CIR Expert Panel has affirmed the safety of polyethylene glycol ingredients, including PEG-240, for use in cosmetics. Higher molecular weight PEGs (PEG-75 and above) exhibit minimal absorption through intact skin, are minimally irritating, and are not considered sensitizers. Initial concerns regarding kidney toxicity were linked to severely burned patients treated with PEG-based creams, but subsequent data clarified that significant penetration occurs only through severely damaged skin (second and third-degree burns); the CIR Expert Panel later removed this caveat. The FDA permits PEGs with an average molecular weight of 6,000 as a food additive, and PEG-240 is approved for general or specific limited food uses in the US. Manufacturers are advised to minimize impurities like ethylene oxide and 1,4-dioxane.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

PEG-240 is a valuable humectant and texture enhancer, offering long-term hydration and barrier support with a low safety risk profile across all skin types, including sensitive.


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