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Moumoujus

PEG-22 DIMETHACRYLATE.

Questionable CAS - / NAIL CONDITIONING

PEG-22 Dimethacrylate is a derivative of polyethylene glycol, engineered as a bifunctional macromer. It is designed to undergo free-radical polymerization, yielding highly crosslinked, hydrophilic hydrogels. In cosmetic applications, its primary utility is anticipated to be in film formation or the modification of product rheology.

Summary

Crosslinking Agent Film Former Rheology Modifier

Science

Mechanism of Action

As a poly(ethylene glycol) dimethacrylate (PEGDMA), this ingredient acts as a bifunctional macromer. Its core mechanism involves free-radical polymerization, which leads to the creation of highly crosslinked, hydrophilic hydrogels. While the polyethylene glycol backbone could theoretically contribute to humectancy by attracting and retaining water, the dimethacrylate functionality predominately dictates its role in forming robust films or modulating the viscosity and texture of formulations upon polymerization.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 2 – 8
0 7 14

Stability

This ingredient exhibits pH stability across a broad range from pH 2 to 8. Formulations should specifically avoid strong oxidizing agents and direct sunlight, as the ingredient may be sensitive to these conditions, potentially compromising stability.

Conflicts

  • strong oxidizing agents
  • sunlight

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk Moderate

The Cosmetic Ingredient Review (CIR) Expert Panel has not issued a specific assessment for PEG-22 Dimethacrylate, classifying it with "insufficient data." However, Safety Data Sheets for poly(ethylene glycol) dimethacrylate indicate it causes skin irritation (H315) and serious eye irritation (H319). A structurally related compound, ethylene glycol dimethacrylate, is considered a moderate skin sensitizer. Furthermore, general PEG derivatives sometimes present contamination concerns with Ethylene Oxide and 1,4-Dioxane.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Medium
Comedogenicity Unknown

Our Assessment

Verdict

Questionable

Due to insufficient specific cosmetic safety data, alongside indications of medium skin and serious eye irritation, and moderate sensitization risk from related compounds, its inclusion in skincare formulations warrants careful consideration and further research.

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