Science
Mechanism of Action
This ingredient operates by reducing the surface tension at the interface of different phases, which allows for the creation and stabilization of emulsions. As a surfactant, it aids in dispersing and removing dirt and oils from surfaces.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Conflicts
- Ingredients whose safety is primarily based on minimal dermal absorption, as PEG-2 Diisostearate (and other PEG diesters) may enhance their skin penetration.
- Application to damaged or compromised skin, as a general precaution for PEGs and their derivatives.
Safety
Safety Profile
The CIR Expert Panel concluded that PEG-2 Diisostearate is safe for cosmetic use when formulated to be non-irritating. However, a significant consideration is its potential to enhance the dermal penetration of other compounds. Formulators must exercise caution when combining this ingredient with others whose safety relies on limited skin absorption. General concerns for PEG-based ingredients include the potential presence of 1,4-dioxane and ethylene oxide impurities, underscoring the necessity of using current Good Manufacturing Practices (cGMPs) to ensure purity. Furthermore, PEGs and their derivatives, including PEG-2 Diisostearate, should not be applied to damaged or compromised skin.
Your Skin
Skin Compatibility
Our Assessment
Verdict
PEG-2 Diisostearate is a valuable ingredient for achieving stable formulations through its emulsifying and surfactant properties, though its use requires careful consideration of potential enhanced dermal penetration and suitability for compromised skin.
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References
Sources