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PEG-15 HYDROGENATED LANOLIN.

Valuable CAS 68648-27-1 / SKIN CONDITIONING - EMOLLIENT, SURFACTANT - EMULSIFYING

PEG-15 Hydrogenated Lanolin is a polyether lanolin derivative that acts primarily as a skin conditioning agent and an emulsifier. It supports skin hydration by forming a protective film and contributes to the stability of cosmetic formulations.

Summary

Emollient Emulsifying Skin Conditioning Hair Conditioning

Science

Mechanism of Action

This ingredient functions as an emollient, lubricating the skin's surface to impart a soft and smooth texture. It forms an occlusive oil film on the stratum corneum, which effectively reduces transepidermal water loss (TEWL), thereby enhancing skin moisture. Furthermore, as a surfactant-emulsifying agent, it stabilizes emulsions by reducing the surface tension between immiscible oil and water phases.

Research

Clinical Evidence

Medium confidence
Effective range 0.001–15%
Optimal

N/A

Key findings

  1. 01 Clinical studies on PEG Lanolins, including PEG-15 Hydrogenated Lanolin, demonstrated mild or negligible skin irritation and were nonsensitizing at concentrations up to 100%.
  2. 02 In patient trials, PEG Lanolins, including PEG-15 Hydrogenated Lanolin, were reported as nonirritating and nonsensitizing at concentrations ranging from 10% to 60%.
  3. 03 Polyether lanolins, including PEG-15 Hydrogenated Lanolin, are utilized in cosmetic products within a concentration range of 0.001% to 15%.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH 2 – 10
0 7 14

Stability

Based on related PEG Lanolins (e.g., PEG-75 Lanolin), this ingredient is stable within a broad pH range of 2 to 10 and exhibits only slight susceptibility to oxidative and reducing agents.

Safety

Safety Profile

CIR Status
Safe as used
Max tested
60%
Sensitization risk Low

The CIR Expert Panel concluded that PEG-Lanolin and PEG-Hydrogenated Lanolin ingredients, including PEG-15 Hydrogenated Lanolin, are safe for use in cosmetics. While 1,4-dioxane is a potential byproduct of the ethoxylation process, its levels can be effectively controlled through purification. The FDA regulates 1,4-dioxane levels in cosmetic products. Although lanolin was designated the 2023 Allergen of the Year, leading to a re-opened CIR safety assessment for lanolin-derived ingredients, the general conclusion regarding the safety of PEG Lanolins remains favorable. The SCCS status is currently unknown.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

PEG-15 Hydrogenated Lanolin is a valuable ingredient for improving skin hydration and stabilizing formulations, demonstrating a low risk of irritation and sensitization across tested concentrations.

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