Science
Mechanism of Action
As an amphiphilic surfactant, PEG-12 DITALLATE functions by reducing the surface tension between immiscible liquids, such as oils and water. This action facilitates the formation and stabilization of emulsions, preventing separation and ensuring uniform distribution of ingredients within cosmetic and personal care products.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Due to its ester nature, PEG-12 DITALLATE is susceptible to hydrolysis, which can compromise its stability in the presence of strong acids or strong alkalis. It is expected to maintain stability in neutral, mildly acidic, or mildly alkaline aqueous solutions. Its amphiphilic character allows it to interact effectively with both aqueous and oil phases.
Conflicts
- Strong acids
- Strong alkalis
- Ingredients whose safety relies on limited dermal absorption, due to potential for enhanced skin penetration
Safety
Safety Profile
The CIR Expert Panel deemed PEG diesters, including PEG-12 DITALLATE, safe for use in cosmetics when formulated to be non-irritating. However, it was noted as not being widely reported in current use at the time of the 2014 CIR assessment. Significant concerns exist regarding potential impurities, including pesticide residues and heavy metals from botanical tall oil sources, as well as manufacturing byproducts like 1,4-dioxane and ethylene oxide. The CIR emphasized strict adherence to current Good Manufacturing Practices (cGMPs) to minimize these contaminants. Formulators must also be aware that PEG diesters can enhance the dermal penetration of other compounds, necessitating careful formulation when combined with ingredients whose safety relies on minimal skin absorption. No specific SCCS or FDA regulatory status was identified.
Your Skin
Skin Compatibility
Our Assessment
Verdict
PEG-12 DITALLATE serves as an effective emulsifying surfactant, yet its use is questionable due to potential impurities and its ability to enhance the dermal penetration of other ingredients, requiring highly careful formulation.
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