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Moumoujus

PEDIOCOCCUS/GYNOSTEMMA PENTAPHYLLUM FERMENT FILTRATE.

Insufficient Data / SKIN CONDITIONING

This ingredient is a sophisticated postbiotic ferment filtrate derived from *Gynostemma pentaphyllum* leaves, meticulously fermented with *Pediococcus*. This process enriches the botanical's natural compounds, yielding a solution packed with beneficial metabolites, enzymes, and organic acids designed to enhance skin health.

Summary

Skin Conditioning Antioxidant Microbiome Support Barrier Reinforcement

Science

Mechanism of Action

The *Gynostemma pentaphyllum* component within the filtrate acts as a potent antioxidant, precisely targeting and reducing oxidative stress on dermal fibroblasts. The *Pediococcus* fermentation significantly augments this antioxidant capacity and amplifies the content of key bioactives, including phenolics and flavonoids. Furthermore, as a ferment filtrate, it delivers a spectrum of postbiotics that contribute to skin conditioning, forming a protective barrier to minimize trans-epidermal water loss. These postbiotics also modulate the skin's micro-ecological activity, fostering a balanced microbiome by inhibiting harmful bacteria and promoting overall skin barrier integrity.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 At 4.5 mg/mL, *Gynostemma pentaphyllum* extract significantly extended the viability of mouse dermal fibroblasts subjected to UVC light, indicating a reduction in oxidative stress, cellular aging, and apoptosis. This protective effect was observed to be dose-dependent.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) Expert Panel has not specifically reviewed Pediococcus/Gynostemma Pentaphyllum Ferment Filtrate. While other ferment-derived ingredients (e.g., certain yeast and *Lactobacillus* ferments up to 5.6%) have been deemed safe for cosmetic use, and lactic acid fermentation products are generally recognized as safe (GRAS) for food by the FDA, these conclusions do not directly apply to the cosmetic safety assessment of this specific ingredient.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

While promising in vitro antioxidant activity and microbiome-balancing benefits are suggested, comprehensive clinical efficacy and safety data for this specific ferment filtrate are currently insufficient for a definitive rating.

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