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PANTHENYL ETHYL ETHER BENZOATE.

Insufficient Data / HAIR CONDITIONING, SKIN CONDITIONING

Panthenyl Ethyl Ether Benzoate is an ester formed from panthenyl ethyl ether and benzoic acid, designed to deliver the benefits of Vitamin B5 to the skin. It works by converting into pantothenic acid within skin cells, which is vital for maintaining skin health and function.

Skin conditioning Enhances skin barrier function Promotes wound healing Modulates inflammatory responses

Science

This compound undergoes bioactivation in skin cells, where its panthenyl ethyl ether component is metabolized into pantothenic acid (Vitamin B5). Pantothenic acid then becomes an essential part of Coenzyme A, a crucial element for fortifying the skin barrier, facilitating wound healing, and modulating inflammatory responses. The benzoate ester enhances the stability and longevity of the compound within cosmetic formulations, ensuring its sustained action.


Research

Insufficient-data confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Both
Optimal pH 5 – 7
0 7 14

Stability

Panthenyl Ethyl Ether Benzoate maintains stability under standard conditions. However, it is susceptible to hydrolysis in highly acidic or highly alkaline environments and can ignite upon contact with strong oxidants. Its design specifically targets cosmetic formulations within a pH range of 5.0 to 7.0 for optimal stability and performance.

Conflicts

  • Strong acids
  • Strong alkalis
  • Strong oxidants
  • Ingredients leading to the formation of N-nitroso compounds if residual amine impurities are present

Safety

CIR Status
Not reviewed
Sensitization risk Unknown

While the Cosmetic Ingredient Review (CIR) Expert Panel has deemed Panthenol, Pantothenic Acid, and several related derivatives (including Panthenyl Ethyl Ether) safe for cosmetic use, Panthenyl Ethyl Ether Benzoate itself has not been explicitly reviewed. The Panel cautioned against using ingredients that may contain residual amine impurities in formulations where N-nitroso compounds could potentially form.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Insufficient Data

While Panthenyl Ethyl Ether Benzoate offers a promising mechanism for skin barrier enhancement, wound healing, and anti-inflammatory effects via conversion to Vitamin B5, specific clinical efficacy data and direct CIR safety review for this particular ester are currently unavailable.


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References