Science
Mechanism of Action
PALMITOYL HYDROXYPROPYLTRIMONIUM AMYLOPECTIN/GLYCERIN CROSSPOLYMER functions by contributing to the structural integrity and comprehensive delivery capabilities of Glycospheres. These supramolecular configurations feature a hydrophilic solid inner core of modified starch, which is then enveloped by a peripheral lipophilic layer due to covalently grafted fatty acids. This unique architecture enables the efficient retention and delivery of lipophilic active agents. Concurrently, the central core of Glycospheres contains strongly cationic groups, allowing for the precise retention of anionic hydrophilic actives through ionic bonds, thereby providing a versatile delivery platform.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
The ingredient demonstrates general stability. When incorporated into Glycospheres, it significantly contributes to improving the stability of both encapsulated and entrapped active molecules, safeguarding their integrity within the formulation.
Synergies
- encapsulated active molecules
- entrapped active molecules
Conflicts
- strong oxidants (in solid form)
Safety
Safety Profile
This ingredient is not listed on EWG's Skin Deep Restricted or Unacceptable Lists, and EWG rates it 'LOW' for concerns related to Cancer, Allergies & Immunotoxicity, and Developmental and Reproductive Toxicity. Currently, specific safety references for AIDS, Cancer, Toxicology, or determinations of oral/dermal/inhalation toxicity are not available, nor are there specific SCCS opinions.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This ingredient is valuable for its dual function as a skin conditioning agent and an integral component of Glycosphere delivery systems, enabling enhanced active ingredient stability and controlled release within formulations.
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References
Sources