Science
Mechanism of Action
This ingredient operates primarily as a humectant, drawing moisture from the environment into the skin and helping to prevent transepidermal water loss. As a derivative of Hydroxypropylcellulose, it also contributes to formulation aesthetics by providing thickening, stabilizing, and film-forming properties, which can further aid in moisture retention.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
The ingredient, based on its Hydroxypropyl Cellulose (HPC) polymer, maintains stability across a broad pH range of 2 to 10. It is soluble in cold water, ethanol, methanol, and various polar organic solvents, with higher degrees of substitution potentially increasing solubility in both water and organic solvents. However, it exhibits insolubility in hot water, specifically above 40-45°C.
Conflicts
- strong oxidizing agents
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel deemed Palmitoyl Hydroxypropylcellulose safe for use, assessing it within a review of Palmitoyl Oligopeptides. Data pertaining to chemistry, production, concentration of use, acute oral toxicity, ocular irritation, skin irritation, sensitization (in both animal and human studies), and genotoxicity were reviewed. Its related compound, Hydroxypropylcellulose (HPC), has been found practically nontoxic and safe for cosmetic use up to 10% concentration and is FDA-approved for certain food and drug applications.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Palmitoyl Hydroxypropylcellulose is a valuable ingredient for enhancing skin hydration and contributing to the optimal stability and texture of cosmetic formulations.
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