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PALMITAMIDOHEXADECANEDIOL.

Insufficient Data CAS 129426-19-3 / SKIN CONDITIONING

PALMITAMIDOHEXADECANEDIOL is a biomimetic lipid, specifically an N-acylhexadecasphinganine, structurally akin to natural ceramides. This ingredient is designed to integrate into the skin's natural barrier, enhancing its integrity and moisture retention capabilities.

Skin Barrier Support Moisture Retention Skin Conditioning

Science

As a ceramide lipid, PALMITAMIDOHEXADECANEDIOL acts by reinforcing the intercellular lipid matrix of the stratum corneum. This structural contribution helps fortify the skin's epidermal barrier function, effectively reducing transepidermal water loss (TEWL) and promoting sustained hydration and improved skin resilience.


Research

Insufficient-data confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Safety

CIR Status
Not reviewed
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) has not yet evaluated PALMITAMIDOHEXADECANEDIOL for safety. Currently, there are no reported GHS classifications, hazard statements, or determined oral, dermal, or inhalation toxicity data. It is recognized as a skin conditioning agent in cosmetics.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Insufficient Data

While its structural classification as a ceramide-like lipid suggests potential benefits for skin barrier integrity, the absence of specific clinical efficacy data and comprehensive safety assessments warrants an insufficient-data rating.


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