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Paecilomyces Japonica/cynanchum Wilfordii Root Ferment Extract Filtrate

This advanced ingredient is a fermented filtrate derived from the symbiotic action of Paecilomyces japonica on Cynanchum wilfordii root. It functions primarily as a skin conditioning agent, hypothesized to deliver antioxidant, anti-inflammatory, and barrier-supportive benefits through its unique metabolic profile.

Directory entry · Individual source review pending

This profile is awaiting an individual source review. Treat its ratings, dose estimates and compatibility labels as provisional; they are not medical advice or proof of a finished product’s effects.

Skin Conditioning Antioxidant Anti-inflammatory Barrier Support

Science

Mechanism of Action

Classified as a skin conditioning agent, this ferment filtrate's mechanism is inferred from its constituent parts. Extracts of *Cynanchum wilfordii* root are recognized for their antioxidant, adaptogenic, and anti-inflammatory properties, with studies demonstrating a dose-dependent suppression of LPS-induced nitrite and prostaglandin E2 (PGE2) production. The fermentation process itself, typical of yeast-derived filtrates, enriches the extract with beneficial metabolites, enzymes, and peptides, which generally contribute to antioxidative defense, improved barrier function, and anti-inflammaging effects.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Unknown
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk Unknown

Comprehensive safety assessments by bodies such as CIR (Cosmetic Ingredient Review) or SCCS (Scientific Committee on Consumer Safety) specifically for PAECILOMYCES JAPONICA/CYNANCHUM WILFORDII ROOT FERMENT EXTRACT FILTRATE are currently unavailable, with its CIR status noted as 'insufficient data'. Some databases identify this as a 'new ingredient' lacking established benefits or safety profiles. While broader assessments exist for certain yeast-derived ingredients (e.g., Lactobacillus Ferment deemed safe up to 5.6%), specific data for this complex ingredient is needed for a definitive safety conclusion.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

While offering theoretical skin conditioning benefits derived from its components and fermentation, the current body of research provides insufficient specific data to fully assess its clinical efficacy and comprehensive safety profile.

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