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P-VINYLPHENOL.

Avoid CAS 2628-17-3 / PERFUMING

P-Vinylphenol, also recognized as 4-Vinylphenol or 4-Hydroxystyrene, is an organic compound with extremely significant hazard classifications. While a glucoside derivative shows potential for skincare benefits, the raw material itself is not suitable for cosmetic applications.

fragrance component perfuming

Science

P-Vinylphenol has been observed to inhibit prostaglandin synthesis, indicating a potential for anti-inflammatory action. However, specific direct cosmetic mechanisms for the raw compound are not well-detailed. Benefits such as antioxidant properties, reduction of skin inflammation, protection from sun damage, and inhibition of melanin production are attributed to its derivative, p-Vinylphenol glucoside, not P-Vinylphenol itself.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

P-Vinylphenol exhibits good stability but is sensitive to light and ozone, which can induce oxidation, decomposition, and polymerization. It is also hygroscopic. Optimal storage requires an inert gas atmosphere (nitrogen or argon) at a temperature range of 2-8°C. Predicted water solubility is approximately 8.4 g/L.


Safety

CIR Status
Not reviewed
Pregnancy
Caution
Sensitization risk High

P-Vinylphenol presents severe safety hazards. It is classified as toxic if swallowed, harmful if swallowed, fatal in contact with skin, and toxic in contact with skin. It causes severe skin burns and eye damage, induces skin irritation, and may provoke an allergic skin reaction. Furthermore, it is fatal if inhaled, may cause allergy or asthma symptoms, or breathing difficulties if inhaled. It is suspected of causing genetic defects and damaging fertility or the unborn child. Prolonged or repeated exposure can lead to organ damage. The FDA no longer permits its use as a synthetic flavoring substance.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Avoid

Due to its severe toxicity, corrosive properties, and potential for genetic and reproductive harm, P-Vinylphenol is unequivocally unsuitable for cosmetic applications and should be entirely avoided.


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