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P-CRESYL SALICYLATE.

Optional CAS 607-88-5 / PERFUMING

P-Cresyl Salicylate is a synthetic salicylate ester primarily utilized in cosmetic formulations for its perfuming qualities. While chemically related to salicylic acid, its main function within skincare is to impart scent, rather than deliver active benefits.

perfuming

Science

This ingredient is an ester formed from p-cresol and salicylic acid. Although salicylic acid is well-documented for its keratolytic, desmolytic, anti-inflammatory, and comedolytic properties, the direct mechanism of P-Cresyl Salicylate as a standalone active for skin treatment is not detailed in current literature. Its primary role in formulations is to act as a fragrance component.


Research

Insufficient-data confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

P-Cresyl Salicylate is predominantly used as a fragrance ingredient. The concept of 'dusting' typically applies to active ingredients whose claimed benefits are not delivered at insufficient concentrations, which is not applicable for a perfuming agent.


The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

It should be stored in a cool, dry environment, protected from direct sunlight and heat. Generally noted for good stability and compatibility within complex fragrance formulations, but like other esters, it may be susceptible to hydrolysis at extreme pH levels.


Safety

CIR Status
Not reviewed
Max tested
0.0115%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has not specifically reviewed P-Cresyl Salicylate. However, its hydrolysis product, Salicylic Acid, has been deemed safe for cosmetic use when non-irritating and non-sensitizing. A Research Institute for Fragrance Materials (RIFM) safety assessment, based on read-across data, suggests P-Cresyl Salicylate is not expected to be genotoxic, phototoxic, or photoallergenic. Dermal sensitization risk is considered low, with exposure levels below the Dermal Sensitization Threshold (DST). An IFRA recommendation limits its use to 0.0115% in cosmetic formulations for its perfuming function.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Optional

P-Cresyl Salicylate is an optional ingredient, valued exclusively for its perfuming properties in cosmetic formulations, with no established active skincare benefits.


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