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Moumoujus

P-AMINOPHENOL HCL.

Avoid CAS 51-78-5 / HAIR DYEING

P-AMINOPHENOL HCL is primarily known as an oxidative hair dye precursor, reacting with an oxidizing agent to form hair color. Its application in skincare is not associated with beneficial effects but rather with potential irritation and sensitization. As such, it is not considered an active ingredient for dermatological treatment.

Summary

Hair Dyeing Precursor

Science

Mechanism of Action

On the skin, P-AMINOPHENOL HCL does not exert beneficial dermatological effects. Instead, its primary mechanism of action involves its role as an oxidative precursor in hair dye formulations, where it reacts with oxidizing agents, such as hydrogen peroxide, to develop color. Direct skin interaction is predominantly characterized by potential irritation and sensitization responses.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

This ingredient is primarily utilized as a hair dye precursor and has no established beneficial dermatological effects. Therefore, the concept of 'dusting' for skin efficacy is not relevant to its profile.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

P-AMINOPHENOL HCL exhibits high solubility in water and is also soluble in alcohol. It is prone to oxidation, particularly in the presence of a base, and is sensitive to degradation from exposure to heat, air, and light. It demonstrates violent reactivity with strong acids, strong bases, alcohols, and amines. Stabilization can be achieved through the inclusion of antioxidants, such as ascorbic acid.

Conflicts

  • Strong acids
  • Strong bases
  • Alcohols
  • Amines
  • Oxidizing agents (unless purposefully used for color development)
  • Exposure to air
  • Light
  • Heat

Safety

Safety Profile

CIR Status
Safe with restrictions
Max tested
0.9%
Sensitization risk High

European and American experts consider p-aminophenol safe for use at authorized concentrations in cosmetic products, specifically with a maximum on-head concentration of 0.9% in oxidative hair dye formulations, apart from its sensitizing potential. P-aminophenol is classified as a mutagen category 2 (CLP) substance. It is suspected of being corrosive for the skin and causing allergies (sensitizing). It caused irritancy on normal skin above a concentration of 2.5%. It is also classified as causing skin irritation, serious eye irritation, and may cause an allergic skin reaction.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Verdict

Avoid

P-AMINOPHENOL HCL is a hair dye precursor with significant risks of skin irritation and sensitization, offering no beneficial effects for skincare applications and should be avoided in precision skincare formulations.

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