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OLEOYLOXYPHENOXY PROPIONIC ACID.

Valuable / ANTIOXIDANT, SKIN CONDITIONING

OLEOYLOXYPHENOXY PROPIONIC ACID is a precision active ingredient engineered to address hyperpigmentation and unify skin tone. It leverages a unique, non-tyrosinase inhibiting pathway to effectively reduce melanin levels, targeting concerns such as age spots and uneven complexions.

skin conditioning skin brightening spot fading melanin formation prevention photoprotective anti-inflammatory

Science

This ingredient precisely decreases melanin production within melanocytes in a dose-dependent manner. Its action occurs via an alternative pathway, as it does not inhibit tyrosinase enzyme activity. It also reduces melanin release, preventing its accumulation within skin cells. Additionally, it confers photoprotective and anti-inflammatory benefits to epidermal keratinocytes, thereby helping to mitigate skin damage induced by UVB irradiation.


Research

High confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Unknown
Optimal pH N/A
0 7 14

Synergies

  • Ellagic acid
  • Yeast extract
  • Salicylic acid

Safety

CIR Status
Not reviewed
Sensitization risk Low

While the Cosmetic Ingredient Review (CIR) has not yet reviewed OLEOYLOXYPHENOXY PROPIONIC ACID, in vitro studies on Hydroxyphenoxy Propionic Acid (a closely related compound) demonstrated no cytotoxicity, even at concentrations 300 times higher than its IC50 for melanin reduction. The New Zealand Environmental Protection Authority (EPA) states that 'Propanoic acid, 2-(4-hydroxyphenoxy)-, (2R)-' does not have an individual approval but may be utilized under an appropriate group standard.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Valuable

OLEOYLOXYPHENOXY PROPIONIC ACID is a valuable ingredient for precisely addressing hyperpigmentation and uneven skin tone, offering significant efficacy comparable to established brighteners with a favorable low irritancy profile across all skin types.


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