Science
Mechanism of Action
This ingredient primarily functions by imparting a distinctive woody, ambergris-like scent, serving to perfume cosmetic formulations and mask undesirable odors on the skin. Its action is centered on scent contribution rather than providing direct dermal physiological benefits.
Research
Clinical Evidence
Insufficient-data confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
The Scientific Committee on Consumer Safety (SCCS) has recommended its inclusion in EU Fragrance Allergens labeling due to reported positive reactions in dermatological patch tests, ranging from 0.2% to 1.7% of patients. It is categorized as a skin irritant (H315 EU CLP) and a skin sensitizer (H317 EU CLP) by European regulations. The International Fragrance Association (IFRA) restricts the use of its most abundant beta-isomer (CAS No. 54464-57-2) in finished products, with concentrations varying from 1.34% to 34% depending on the product category. Animal toxicity studies showed skin lesions in rats at a lowest-observed-effect level (LOEL) of 12.5% and in mice at 6.25%, with increased relative liver weights also observed in mice. It is not considered toxic or a CMR substance.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Due to its documented classification as both a skin irritant and a skin sensitizer, OCTAHYDRO-TETRAMETHYL-METHANO-1-NAPHTHOL is not recommended for precision skincare formulations focused on optimal skin health.
Related
Similar Ingredients
Finding similar ingredients…