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Moumoujus

OCIMUM BASILICUM OIL.

Valuable CAS 84775-71-3 / 8015-73-4 / FRAGRANCE, TONIC

Ocimum Basilicum Oil, derived from basil, is a potent essential oil with multifaceted benefits for skin. It acts as a strong antioxidant, anti-inflammatory, and antimicrobial agent, effectively combating acne-causing bacteria and reducing oxidative stress. Its astringent properties also help purify and tighten pores, contributing to a clearer and more balanced complexion.

Summary

Masking Tonic Antioxidant Anti-inflammatory Antimicrobial Astringent Hydrating Moisturizing

Science

Mechanism of Action

This oil modulates inflammation through robust antioxidant activity, scavenging free radicals and boosting endogenous antioxidants. It suppresses pro-inflammatory cytokines (e.g., TNF-α, IL-6, IL-17) and inhibits inflammatory mediators like nitric oxide, prostaglandins, and NF-κB, with Linalool specifically targeting the NF-κB pathway. Potent antimicrobial activity against Propionibacterium acnes is achieved by disrupting microbial cell membranes, inhibiting biofilm formation, and causing intracellular leakage. The oil also provides astringent properties for pore refinement and offers hydrating effects.

Research

Clinical Evidence

Medium confidence
Effective range 2–3%
Optimal

3%

Key findings

  1. 01 A 3% Ocimum basilicum microemulsion demonstrated safety and effective antimicrobial activity against Propionibacterium acnes, proving to be the most effective concentration for acne treatment in human skin studies.
  2. 02 Products containing 2% Ocimum essential oils were found to be safe and non-irritating on human skin, while concentrations of 5% caused irritation.

Transparency

Dusting Analysis

Commonly dusted
Min. effective
3%
Red flag below
5%

Ocimum Basilicum Oil poses a significant risk for irritation and sensitization when used in concentrations exceeding 3% or if the oil oxidizes. Formulations that do not explicitly mention stabilization with antioxidants or precise concentration control should be approached with caution due to the ingredient's documented potential for adverse skin reactions, including contact allergen status by SCCS.

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

To prevent oxidation, which leads to skin sensitization, it is crucial to incorporate antioxidants (e.g., 0.1% BHT or alpha-tocopherol) during raw material production, ensuring peroxide levels remain below 20 mmol/l. The oil should be integrated into formulations during the cooling-down phase.

Conflicts

  • strong oxidizing agents (leads to sensitization)

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
3%
Sensitization risk High

While generally recognized as safe (GRAS) by the FDA as a food additive and listed for cosmetics under FDA PART 182, Ocimum Basilicum Oil contains estragole, a potential procarcinogen. Medicinal doses are not recommended during lactation. The European Commission's SCCS identifies it as an established human contact allergen, and ECHA classifies it as potentially causing serious eye irritation, skin irritation, and allergic skin reactions, particularly as an oxidised sensitizer.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Medium
Comedogenicity Low

Our Assessment

Verdict

Valuable

Ocimum Basilicum Oil is a valuable ingredient for its potent anti-inflammatory, antioxidant, and antimicrobial properties, particularly in acne treatments, but demands precise formulation at or below a 3% concentration and stabilization with antioxidants to ensure safety and prevent irritation or sensitization.

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