Science
Mechanism of Action
This ingredient's mechanism of action is specifically within oxidative hair dyeing processes, where it acts as a precursor that reacts to form the desired hair color. There is no established mechanism of action or efficacy for skin-specific benefits.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
O-Aminophenol is primarily utilized for its coloring properties in hair dyes and is not an ingredient commonly 'dusted' or overused in typical skincare applications, nor does it have established skincare benefits that would warrant such use.
The Formula
Formulation
Stability
O-Aminophenol exhibits stability but is sensitive to both air and light exposure, which can cause it to develop a gray or brown discoloration. It requires storage in a tightly sealed container, protected from light, to maintain its integrity.
Conflicts
- strong oxidizing agents
- air
- light
- THF (tetrahydrofuran)
Safety
Safety Profile
The SCCS regulates O-Aminophenol for use as an oxidative hair dye, permitting a maximum concentration of 2% in finished cosmetic products and 0.6% on the head. Despite the CIR Expert Panel concluding its safety for hair dye use, it is classified as a mutagen (category 3). Concerns exist that it can metabolize into genotoxic compounds when glutathione levels are low. EWG Skin Deep identifies high use restrictions, deeming it 'Unacceptable' for EWG VERIFIED products due to concerns including potential cancer risk (mutagen - limited evidence), moderate allergy and immunotoxicity (strong evidence of human skin toxicant/allergen), and high overall use restrictions.
Your Skin
Skin Compatibility
Our Assessment
Verdict
O-Aminophenol is an ingredient for hair dye, presenting significant safety concerns including high irritancy and mutagenicity classification, rendering it unsuitable for precision skincare formulations.
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