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NONA-2,4-DIENAL.

Avoid CAS 6750-03-4 / PERFUMING

NONA-2,4-DIENAL is an aldehyde valued for its fresh, green, and subtly citrusy aromatic profile. Despite its perfuming qualities, it is definitively classified as a potent skin sensitizer and irritant, prohibiting its use in topical applications.

Perfuming agent

Science

On the skin, NONA-2,4-DIENAL's primary interaction is as a perfuming agent, delivering a distinct green and citrus-like scent. Its inherent aldehyde chemical structure is implicated in its recognized capacity to induce dermal sensitization.


Research

Insufficient-data confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

The ingredient exhibits light sensitivity.

Conflicts

  • Primary amines (due to aldehyde reactivity)

Safety

CIR Status
Not reviewed
Max tested
0%
Sensitization risk High

The Expert Panel for Fragrance Safety (IFRA) strongly advises against the use of 2,4-Dienals, including NONA-2,4-DIENAL, as or in fragrance ingredients in any finished product application due to insufficient safety data. The European Chemicals Agency (ECHA) classifies it as a Skin Sensitizer Category 1 (H317: May cause an allergic skin reaction) and notes it as 'Irritating to skin' (R 38). Although the Joint FAO/WHO Expert Committee on Food Additives (JECFA) found no safety concern for its use as a food flavoring agent, this assessment is not applicable to skin exposure. Consequently, its maximum recommended concentration in cosmetic products is 0%.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Low

Our Assessment

Avoid

Due to its established classification as a potent skin sensitizer and irritant, coupled with a recommended maximum cosmetic concentration of 0%, NONA-2,4-DIENAL is unequivocally avoided in precision skincare formulations.


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