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NICOTINOYL PEG-5 TOCOPHERYL SUCCINATE.

Insufficient Data / ANTI-SEBUM, ANTIOXIDANT

NICOTINOYL PEG-5 TOCOPHERYL SUCCINATE is a specialized derivative of Vitamin E, meticulously engineered for enhanced stability and water solubility. It actively functions as an anti-sebum agent and a potent antioxidant, contributing to balanced and protected skin.

Summary

Antioxidant Anti-sebum

Science

Mechanism of Action

This ingredient operates via a dual mechanism: it significantly reduces sebum production, thereby acting as an effective anti-sebum agent. Concurrently, its tocopheryl component delivers robust antioxidant benefits by inhibiting oxygen-promoted reactions, which prevents cellular oxidation and protects skin lipids from environmental aggressors such as pollution. The PEG moiety specifically enhances its solubility and facilitates optimal delivery into the skin.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

NICOTINOYL PEG-5 TOCOPHERYL SUCCINATE exhibits excellent stability against typical environmental stressors like oxygen, heat, and light, ensuring its efficacy as a Vitamin E derivative. However, it is sensitive to alkaline conditions. Related succinate forms of tocopherol, such as Tocopheryl Polyethylene Glycol 1000 Succinate (TPGS), have shown high stability in acidic environments, with only a 3.4% (± 0.4%) degradation over 8 hours at pH 1.0.

Conflicts

  • Alkali

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

While NICOTINOYL PEG-5 TOCOPHERYL SUCCINATE has not been specifically evaluated by the Cosmetic Ingredient Review (CIR) Expert Panel, the safety of numerous related tocopherol derivatives, including Tocopherol, Tocopheryl Nicotinate, Tocopheryl Succinate, and Tocophersolan, has been affirmed for cosmetic use. These closely related compounds have consistently demonstrated a low potential for irritation or sensitization in clinical assessments. For example, Tocopheryl Succinate was deemed safe for concentrations up to 0.038%.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

NICOTINOYL PEG-5 TOCOPHERYL SUCCINATE is a promising stable Vitamin E derivative offering anti-sebum and antioxidant benefits, yet specific clinical efficacy data for this exact compound is currently limited.

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