Science
Mechanism of Action
This ingredient functions by contributing to the olfactory profile of a product, enhancing its sensory experience without a direct biological mechanism of action on the skin itself.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
This ingredient is not associated with dusting concerns in skincare formulations.
The Formula
Formulation
Stability
NERYL ISOVALERATEATE is insoluble in water, but readily soluble in various organic solvents including alcohol (e.g., 1 ml in 8 ml of 80% alcohol), dipropylene glycol, ethanol, methanol, isopropanol, ethyl acetate, chloroform, and THF. For optimal stability, it should be stored at room temperature, protected from heat, moisture, sunlight, and other reactive substances. It is particularly noted for its use in alkaline specialty formulations.
Safety
Safety Profile
NERYL ISOVALERATEATE (also known as Neryl Isovalerate) is Generally Recognized As Safe (GRAS) by the FDA for food use as a flavoring agent (FEMA No. 2778). In human experience, a 6% solution showed no irritation or sensitization. However, GHS classification indicates potential to cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335) for 97.5% of reports. The 6% human experience suggests a low sensitization risk at this concentration, but the GHS warnings indicate a broader potential for irritation.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Due to its classification as a moderate skin irritant based on GHS data and the absence of any identified skincare benefits, NERYL ISOVALERATEATE is not recommended for precision skincare formulations.
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References
Sources