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NERYL ACETATE.

Valuable CAS 141-12-8 / PERFUMING

Neryl Acetate is an ester distinguished by its skin-conditioning properties, primarily focused on enhancing the integrity of the skin barrier. It effectively boosts the production of essential lipids and ceramides, alongside promoting healthy epidermal differentiation and cell cohesion.

Fragrance Skin conditioning Skin barrier strengthening Ceramide synthesis Epidermal differentiation promotion Wound healing support

Science

Neryl Acetate operates by strengthening the skin's natural barrier. It achieves this through stimulating the synthesis of crucial lipids and ceramides within the stratum corneum, mediated by specific ceramide synthesis enzymes. The ingredient further promotes robust epidermal differentiation and cell cohesion, partly by upregulating key proteins like Involucrin (IVL). Additionally, it may support epidermal wound healing by inducing growth factors such as HB-EGF and EREG.


Research

Medium confidence
Effective range N/A
Optimal

0.03%


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH 4 – 8
0 7 14

Stability

Neryl Acetate, an ester, exhibits optimal stability within a pH range of 4.0 to 8.0. While susceptible to hydrolysis in extreme acidic or alkaline conditions, it demonstrates good stability in most cosmetic matrices. Its moderate stability towards alkaline environments permits its inclusion in soap formulations, although highly alkaline systems should be approached with caution.


Safety

CIR Status
Not reviewed
Max tested
5%
Sensitization risk Moderate

Neryl Acetate has not been independently reviewed by the Cosmetic Ingredient Review (CIR), although Achillea millefolium, a constituent, has been. The Scientific Committee on Consumer Safety (SCCS) notes that esters like Neryl Acetate (a cis isomer of geranyl acetate) can hydrolyze in the skin to their parent alcohols, which may act as contact allergens. However, it is designated Generally Recognized As Safe (GRAS) by the FDA for food flavoring. The European Chemicals Agency (ECHA) indicates limited evidence of skin toxicity or allergies and classifies it as not expected to be potentially toxic or harmful. A maximum concentration of 5% reflects typical use in fragrance compositions.


Your Skin

No Normal
Yes Dry
No Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Valuable

Neryl Acetate is a valuable skin conditioning agent, particularly beneficial for strengthening the skin barrier through lipid and ceramide synthesis, while also contributing a pleasant fragrance.


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