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NEROL OXIDE.

Questionable CAS 1786-08-9 / PERFUMING

Nerol Oxide is a synthetic compound primarily valued for its aromatic contribution in cosmetic formulations. Preliminary research indicates potential anti-inflammatory and antioxidant activities, though these benefits for skin health require further clinical validation. Due to its classification as an irritant, precise dilution is critical for topical applications.

fragrance ingredient potential anti-inflammatory potential antioxidant

Science

Nerol Oxide is currently under investigation for its potential to exert anti-inflammatory and antioxidant effects, which may offer protective benefits against inflammatory processes and oxidative cellular damage. The specific biological pathways governing these actions in cutaneous tissue are not yet fully established.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

To preserve its integrity, Nerol Oxide should be stored in a cool, dry, and well-ventilated environment. It must be tightly sealed under an inert gas and protected from extreme sunlight, water, and potent oxidizing agents.

Conflicts

  • extreme sunlight
  • powerful oxygenizing agents

Safety

CIR Status
Not reviewed
Max tested
2%
Sensitization risk Low

A RIFM assessment found Nerol Oxide to be negative for cytotoxicity and genotoxicity, indicating a low concern for skin sensitization. However, it is classified as an irritant (R 36/38) and requires substantial dilution before direct skin application. The FDA also lists it as a flavoring agent.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Questionable

While Nerol Oxide shows nascent potential for antioxidant and anti-inflammatory benefits, its primary application remains as a fragrance. Given its classification as an irritant and lack of conclusive clinical efficacy data for skin, its inclusion for targeted skin benefits in precision skincare is questionable.


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