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Moumoujus

N-VALPROYL SERINOL.

Insufficient Data CAS 1553451-04-9 / EMULSION STABILISING, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

N-VALPROYL SERINOL is a novel N-acylated compound derived from valproic acid and serinol. While its foundational components hint at potential biological activities, direct research on its specific applications and efficacy in topical skincare is presently unavailable.

Summary

Science

Mechanism of Action

The precise mechanism of N-VALPROYL SERINOL on the skin is currently undefined. However, based on the known pharmacology of valproic acid and its derivatives, potential actions may include the strengthening of GABAergic transmission, inhibition of sodium and calcium ion channels, and histone deacetylase (HDAC) inhibition. These mechanisms are typically observed in a systemic context for pharmaceutical derivatives and have not been specifically confirmed for topical N-VALPROYL SERINOL within dermatological applications, where they could theoretically influence cellular processes and gene expression.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Unknown
Optimal pH N/A
0 7 14

Stability

Serinol, the backbone molecule, is characterized as very stable, hygroscopic, and highly water-soluble. Related compounds like valproate sodium solutions (20 mg/mL in 0.9% sodium chloride) have shown physical and chemical stability for at least 30 days when stored at 5°C ± 3°C, with pH stable around 7.01 (range 4.43 – 7.49). However, the specific optimal pH range and stability for N-VALPROYL SERINOL, an N-acylated derivative, are not directly documented and may differ.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

No specific safety assessments for N-VALPROYL SERINOL by major regulatory bodies such as the Cosmetic Ingredient Review (CIR), SCCS, or FDA have been found. Valproic acid, a constituent of this derivative, is a prescription medication with well-documented systemic side effects and therapeutic considerations. Therefore, a comprehensive and specific evaluation of N-VALPROYL SERINOL's safety for topical cosmetic application is essential and currently lacking. N-Palmitoyl Serinol, a distinct serinol derivative, is noted as an FDA-registered Type IV Drug Master File, but this does not directly apply to N-VALPROYL SERINOL.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

Due to a complete lack of specific clinical efficacy data, dermatological mechanism of action, and comprehensive safety assessments for topical application, N-VALPROYL SERINOL's utility in skincare is highly questionable without extensive further research.

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