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Moumoujus

N,N'-METHYLENEBISACRYLAMIDE.

Avoid CAS 110-26-9 / NOT REPORTED

N,N'-METHYLENEBISACRYLAMIDE is a synthetic organic compound that functions primarily as a cross-linking agent. It facilitates the formation of a robust, three-dimensional polymer network, which enhances the structural integrity and firmness of various materials.

Summary

Viscosity Controlling Film-Forming

Science

Mechanism of Action

This ingredient operates by chemically bonding individual polymer chains through covalent links during a polymerization process. The resulting cross-linked architecture significantly boosts the material's internal cohesion and mechanical strength, creating a stable network.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

N,N'-METHYLENEBISACRYLAMIDE exhibits very slight water solubility, specifically 20 g/L at 20°C, and is also soluble in ethanol and acetone. It is prone to oxidation upon prolonged exposure to air and can undergo undesirable polymerization in the presence of moisture. Its aqueous solutions may hydrolyze, producing acrylic acid and ammonia. For optimal stability, storage should be in air-tight containers below 25°C (77°F).

Conflicts

  • strong oxidizers
  • strong acids
  • strong bases
  • air (long-term exposure)
  • moisture

Safety

Safety Profile

CIR Status
Not reviewed
Pregnancy
Caution
Sensitization risk High

This ingredient is classified as a hazardous substance by OSHA. It carries a high risk for skin and eye irritation, dermatitis, and sensitization with prolonged or repeated exposure. The Denmark Advisory list for dangerous substances indicates possible carcinogenicity (Carc3; R40), mutagenicity (Mut3; R68), and reprotoxicity (Rep3; R63). Animal studies suggest potential reproductive disorders, and it can cause genetic defects and organ damage through prolonged or repeated exposure. Respiratory irritation is also a concern, with limited evidence for cumulative effects.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Verdict

Avoid

Due to its high irritancy, significant sensitization potential, and serious safety concerns including potential carcinogenicity, mutagenicity, and reprotoxicity, coupled with a lack of specific clinical efficacy in skincare, N,N'-METHYLENEBISACRYLAMIDE is not recommended for cosmetic formulations.

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