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N,N-DIETHYLTOLUENE-2,5-DIAMINE HCL.

Avoid CAS 2051-79-8 / HAIR DYEING

N,N-DIETHYLTOLUENE-2,5-DIAMINE HCL is a chemical compound primarily employed as a color developing agent in hair dyes and photographic processes. While it serves specific industrial applications, it offers no known beneficial mechanisms for the skin and is definitively classified as a strong skin sensitizer.

Summary

Hair Dye

Science

Mechanism of Action

This compound primarily functions as a reactive agent for color development, notably in hair coloring. On skin, it does not exert any beneficial mechanism of action; rather, safety assessments indicate its potential to act as a potent sensitizer, capable of inducing allergic reactions and significant irritation.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

N,N-DIETHYLTOLUENE-2,5-DIAMINE HCL is an industrial and hair dye intermediate, not an ingredient typically 'dusted' into skincare formulations for perceived benefits. Its documented classification as a strong skin sensitizer unequivocally indicates it has no appropriate role in precision skincare products.

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Related compounds like Toluene-2,5-diamine readily undergo oxidation in neutral or alkaline solutions, forming undesirable dark products. This suggests improved stability in acidic environments. General storage for diethyl toluene diamine derivatives recommends sealed containers in a ventilated, dry, and cool place.

Conflicts

  • Strong acids (forms salts)
  • Strong oxidizers
  • Alkaline solutions (leads to oxidation and discoloration)

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk High

N,N-DIETHYLTOLUENE-2,5-DIAMINE HCL itself has not been directly reviewed by the CIR Expert Panel or SCCS. However, it is classified under 'Cosmetics -> Hair dyeing' in the EUCOSMETICS inventory and is specifically noted to cause skin sensitization. Reviews of related compounds like Toluene-2,5-diamine highlight a strong skin sensitizer potential, with the SCCS previously concluding that concentrations up to 4.0% (free base) were not safe due to a low Margin of Safety, later proposing up to 2.0% for specific hair dye applications.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Verdict

Avoid

Due to its established classification as a strong skin sensitizer and complete absence of any beneficial skincare mechanisms, N,N-DIETHYLTOLUENE-2,5-DIAMINE HCL should be strictly avoided in all skincare formulations.

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