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N-LINOLEOYL SERINOL.

Insufficient Data CAS 72826-67-6 / SKIN CONDITIONING

N-Linoleoyl serinol is a skin-conditioning agent, leveraging its linoleoyl component to enhance the skin barrier through ceramide incorporation, regulation of epidermal processes, and lipid synthesis, thereby supporting skin hydration and integrity.

Skin Conditioning Skin Protecting Barrier Support Hydrating

Science

Functioning as a sophisticated skin conditioning agent, N-Linoleoyl serinol contributes significantly to maintaining skin health. Its core mechanism involves the delivery of the linoleoyl moiety, which is intrinsically linked to linoleic acid. This essential fatty acid is crucial for bolstering the skin's epidermal barrier by facilitating its integration into natural ceramides, modulating epidermal cell differentiation, and stimulating the production of skin lipids. Studies on structurally similar ceramide analogs, such as N-palmitoyl serinol, further support its potential to improve barrier function and encourage intrinsic ceramide synthesis.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

While the serinol backbone demonstrates inherent stability, the linoleoyl component, derived from linoleic acid, is susceptible to oxidation. Consequently, incorporating suitable antioxidants into formulations is advisable to enhance overall product stability and preserve ingredient efficacy.


Safety

CIR Status
Not reviewed
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) Expert Panel has not specifically reviewed N-Linoleoyl serinol. However, structurally analogous ingredients, such as N-palmitoyl serinol, have been registered with the FDA as a Type IV Drug Master File, suggesting a recognized profile for related compounds.


Your Skin

Yes Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Insufficient Data

N-Linoleoyl serinol exhibits promising inferred benefits for skin barrier support and conditioning, yet direct clinical efficacy studies and comprehensive safety reviews are currently limited.


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