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Moumoujus

N-ACETYL DIHYDROSPHINGOSINE.

Insufficient Data CAS 13031-64-6 / HAIR CONDITIONING, SKIN CONDITIONING

N-Acetyl Dihydrosphingosine is a dihydroceramide, a class of lipids crucial for maintaining the skin's barrier integrity. It functions as a skin conditioning agent, supporting epidermal health and moisture retention.

Summary

hair conditioning skin conditioning

Science

Mechanism of Action

As a structural component of the skin's natural lipid barrier, N-Acetyl Dihydrosphingosine actively contributes to the integrity of the stratum corneum. Its mechanism involves reinforcing and replenishing this vital barrier, thereby enhancing moisture retention, improving hydration, and bolstering the skin's intrinsic protective functions against external irritants.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Unknown
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk Unknown

The CIR Expert Panel noted insufficient data for N-Acetyl Dihydrosphingosine in a 2014 Draft Tentative Safety Assessment. Additional critical information requested includes detailed manufacturing methods, impurity profiles, typical use concentrations, comprehensive dermal absorption studies, and, if absorbed, data on reproductive and developmental toxicity, genotoxicity, and dermal irritation/sensitization.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

While recognized for its potential role in reinforcing the skin barrier as a ceramide, a significant lack of comprehensive safety and clinical data warrants a cautious assessment for precision skincare formulations.

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