Science
Mechanism of Action
This botanical resin is noted for its mild antiseptic, antifungal, and antiparasitic properties, contributing to its historical use in various topical applications. It also functions as a skin conditioning agent, aiming to support the skin's overall condition.
Research
Clinical Evidence
Low confidenceN/A
Key findings
- 01 In patch tests on dogs, a 25% concentration in petrolatum was evaluated as a negligible irritant (PDII between 0.025 and 0.350); however, this study focused on irritancy rather than efficacy for skin benefits.
- 02 Human patch tests reveal that Myroxylon pereirae resin frequently causes allergic contact dermatitis, with prevalence rates observed at approximately 3.6% and 5.79% in large studies, and clinical relevance noted in 75.2% of positive cases.
Transparency
Dusting Analysis
Due to its potent sensitizing potential, regulatory bodies such as the SCCS and IFRA strictly recommend that this extract should not exceed a total level of 0.4% in cosmetic products. Crude Peru Balsam is prohibited as a fragrance ingredient due to its classification as an allergen.
The Formula
Formulation
Stability
Myroxylon pereirae resin exhibits a viscous, tar-like consistency, becoming pourable when subjected to heat. It possesses high olfactory tenacity, and its aromatic profile can be enhanced in blends when combined with fixatives such as labdanum or oakmoss.
Synergies
- Labdanum (as an aromatic fixative)
- Oakmoss (as an aromatic fixative)
Conflicts
- Balsam of Tolu
- Beeswax
- Benzaldehyde
- Benzoates
- Benzoin
- Benzyl salicylate
- Coniferyl alcohol
- Coumarin
- Diethylstilbestrol
- Eugenol
- Farnesol
- Isoeugenol
- Propanidid
- Propolis
- Styrax
- Tiger balm
- Fragrance Mix I (FM1) constituents
- Sorbitan Sesquioleate (SSO)
Safety
Safety Profile
The Scientific Committee on Consumer Products (SCCS) and the International Fragrance Association (IFRA) recommend that concentrations of extracts and distillates of Peru balsam do not exceed 0.4% in cosmetic products due to its sensitizing potential. It is classified as an allergen and is a frequent cause of allergic contact dermatitis. Crude Peru Balsam is explicitly prohibited as a fragrance ingredient. The FDA lists it as safe for general or specific, limited use in food, which differs from its cosmetic application safety profile.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Given the exceptionally high risk of allergic contact dermatitis and stringent regulatory limitations on its concentration, Myroxylon pereirae Resin Extract is not recommended for use in precision skincare formulations.
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