Science
Mechanism of Action
This resin exhibits mild bactericidal, fungicidal, and antiseptic activities, attributed to components such as benzoic and cinnamic acids and their esters. It is also noted for its potential to stimulate capillary beds and enhance skin penetration, mechanisms supporting its traditional use in minor wound care.
Research
Clinical Evidence
Low confidenceN/A
Key findings
- 01 Traditional topical applications include aiding the healing of minor wounds, burns, chaps, and various skin inflammations. In vitro assays have demonstrated antibacterial and fungicidal/fungistatic effects against tested microorganisms.
Transparency
Dusting Analysis
A 25% concentration of Peru balsam in patch testing frequently induces allergic contact dermatitis, indicating a substantial risk of sensitization. Regulatory bodies like the SCCS and IFRA have imposed restrictions due to its classification as a known human toxicant and allergen, making it unsuitable for a precision skincare approach.
The Formula
Formulation
Stability
As a resinous material with a significant volatile oil content (cinnamein) and various organic acids and esters, Myroxylon Balsamum Resin is oil-soluble and generally stable under typical cosmetic formulation conditions. It becomes more pourable upon heating.
Conflicts
- Known to cause allergic contact dermatitis and sensitization, particularly in individuals sensitive to fragrances. It contains several prominent allergenic compounds, including isoeugenol, eugenol, and cinnamyl alcohol.
Safety
Safety Profile
The Scientific Committee on Consumer Safety (SCCS) has identified Peru balsam as posing a high risk of sensitization to consumers. Consequently, both the EU Cosmetics Directive and the International Fragrance Association (IFRA) have restricted its use and concentration in cosmetics due to documented concerns regarding allergies, immunotoxicity, and potential for human toxicity. It no longer holds FEMA GRAS™ status for food additives.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Despite its traditional antimicrobial uses, Myroxylon Balsamum Resin carries a high risk of sensitization and allergic contact dermatitis, making it unsuitable for use in precision skincare formulations.
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References
Sources