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Moumoujus

MYRISTOYL DIPEPTIDE-13.

Valuable / SKIN CONDITIONING

Myristoyl Dipeptide-13 is a highly lipophilic dipeptide, designed to enhance penetration into deeper skin layers. It targets cellular proliferation and synthesis of key structural proteins, with notable applications in both skin rejuvenation and hair follicle support.

Summary

Cell Proliferation Collagen Synthesis Elastin Synthesis Wound Healing Re-epithelialization Hair Growth Stimulation Anti-Hair Loss Melanin Synthesis Anti-aging

Science

Mechanism of Action

This ingredient, a lipo-derivative of Dipeptide-13, leverages its myristoyl group to increase lipophilicity, facilitating improved interaction with the skin's lipid-rich architecture and deeper delivery. Once penetrated, it stimulates the proliferation of vital skin cells including dermal papilla cells, fibroblasts, and keratinocytes. It further promotes melanin synthesis in melanocytes and enhances the production of collagen and elastin, contributing to improved skin firmness and elasticity. For hair, it works to prolong the anagen (growth) phase and delay the catagen (regression) phase, supporting hair health and growth.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 In vitro studies demonstrate the peptide's ability to promote the proliferation of dermal papilla cells, fibroblasts, and keratinocytes, alongside an increase in melanin production.
  2. 02 In vivo studies suggest an inhibitory effect on hair loss, leading to strengthened hair and promotion of regrowth.
  3. 03 The peptide stimulates dermal fibroblasts, accelerating both wound healing processes and re-epithelialization in skin.

Transparency

Dusting Analysis

Not commonly dusted

No data suggests this ingredient is commonly 'dusted' in formulations; its specific peptide structure implies targeted biological activity at lower concentrations.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Specific optimal pH ranges or detailed stability data for Myristoyl Dipeptide-13 were not found in the available research.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

No specific safety assessments by the Cosmetic Ingredient Review (CIR), Scientific Committee on Consumer Safety (SCCS), or Food and Drug Administration (FDA) were identified for Myristoyl Dipeptide-13. While reports exist for other Myristoyl-peptides, data for this specific ingredient is currently unavailable.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Myristoyl Dipeptide-13 demonstrates promising in vitro and in vivo efficacy for skin rejuvenation and hair health, though specific optimal concentrations for human application and comprehensive safety reviews remain to be established.

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