Science
Mechanism of Action
As a cationic surfactant, Myristalkonium Chloride disrupts microbial cell membranes by binding to negatively charged phospholipids and proteins. This action increases membrane permeability, leading to leakage of cellular contents, inhibition of enzyme activity, and protein denaturation, ultimately resulting in microbial cell death. On skin, its antimicrobial properties contribute to antiseptic applications.
Research
Clinical Evidence
Insufficient-data confidenceN/A
Transparency
Dusting Analysis
Myristalkonium Chloride functions critically as a preservative to ensure product stability and safety by inhibiting microbial proliferation. It is not an ingredient typically 'dusted' or promoted as a primary active for direct skin benefits, as its efficacy pertains to product integrity rather than skin transformation.
The Formula
Formulation
Stability
An optimal pH range for stability was not specifically identified in the research. However, studies investigating structurally similar compounds like benzalkonium chloride have utilized acidic conditions (e.g., pH 3.5), suggesting potential stability in such environments.
Conflicts
- strong oxidizing agents
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel concluded that Myristalkonium Chloride is safe for cosmetic use at concentrations up to 0.1% of the free active ingredient, based on its structural similarity to Benzalkonium Chloride. It is regulated as a preservative in the EU under EC Cosmetics Regulation (No. 1223/2009) Annex V, with defined maximum concentrations. The ingredient is currently under re-review by the CIR Expert Panel.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Myristalkonium Chloride is a valuable ingredient primarily for its preservative and antimicrobial properties, essential for maintaining the safety and integrity of cosmetic formulations at concentrations up to 0.1%.
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References
Sources