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Moumoujus

METSCHNIKOWIA HENANENSIS EXTRACT.

Insufficient Data / HUMECTANT, SKIN CONDITIONING

Metschnikowia Henanensis Extract is classified as a skin-conditioning agent, primarily functioning as a humectant to attract and retain moisture. While other species within its genus show promising effects on skin microbiota and hydration, specific data for this extract's efficacy and safety remain largely undefined.

Summary

Skin-Conditioning Agent Humectant

Science

Mechanism of Action

This extract is categorized as a humectant, working to draw moisture from the surrounding environment into the skin, thereby promoting enhanced hydration. Broader research on other *Metschnikowia* species suggests potential for modulating skin microbiota, boosting hyaluronic acid synthesis (via HAS2), and exhibiting antimicrobial activity through the production of pulcherrimin. However, these specific advanced benefits have not been directly substantiated for *Metschnikowia Henanensis Extract* itself within the current available data.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Unknown
Optimal pH N/A
0 7 14

Stability

General considerations for yeast-derived ingredients indicate that manufacturing processes are designed to render yeast non-viable. These processes typically involve high temperatures (exceeding 50°C for bulk manufacturing and up to 80°C for enzymatic inactivation), atomization, the incorporation of preservatives, and freezing to ensure stability and safety.

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) Expert Panel issued a second Insufficient Data Announcement (IDA) for Metschnikowia Henanensis Extract in June 2023. As of June 2024, the CIR Panel continues to deem the data insufficient for a safety determination, specifically requesting confirmatory dermal sensitization data. Alternatively, data on its Generally Recognized As Safe (GRAS) or Qualified Presumption of Safety (QPS) status for food use, or 28-day dermal toxicity data, could be submitted. Currently, no cosmetic uses for this ingredient have been reported.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

While classified as a humectant, the absence of specific safety and efficacy data for Metschnikowia Henanensis Extract, coupled with the CIR Panel's ongoing request for further information, currently renders its suitability for cosmetic applications highly questionable.

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