Science
Mechanism of Action
Methylundecanal interacts with olfactory receptors to create a sensory experience. In topical applications, its role is confined to contributing a specific fragrance. The available data does not indicate any direct mechanism of action that confers therapeutic benefits to the skin.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
Methylundecanal serves exclusively as a fragrance component; therefore, 'dusting' related to therapeutic efficacy thresholds is not applicable to its use.
The Formula
Formulation
Stability
This ingredient is soluble in various oils (fixed oils, paraffin oil), alcohols (ethanol, propylene glycol, dipropylene glycol), glycols, silicones, and DMSO. It demonstrates limited solubility in water and glycerin. For optimal formulation, Methylundecanal should be incorporated into the oil phase, with processing temperatures kept below 60°C. It exhibits robust stability across a wide range of product types including alkalis, amines, ammonia, antiperspirants, creams, and shampoos.
Safety
Safety Profile
Methylundecanal is Generally Recognized as Safe (GRAS) by the FDA when used as a flavoring agent in food. Safety assessments by the Research Institute for Fragrance Materials (RIFM) indicate a favorable Margin of Exposure (>100) for repeated dose and reproductive toxicity, and a No Expected Sensitization Induction Level (NESIL) of 2900 μg/cm² for skin sensitization. However, the European Chemicals Agency (ECHA) GHS classification notes that it can cause skin irritation (H315) and may cause an allergic skin reaction (H317). The European Commission's Scientific Committee on Consumer Safety (SCCS) has highlighted a lack of human contact allergy data for this substance.
Your Skin
Skin Compatibility
Our Assessment
Verdict
While often used for its appealing scent, Methylundecanal offers no skin benefits and carries a moderate risk of skin irritation and allergic reaction, making its inclusion in precision skincare formulations questionable.
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