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METHYLUNDECANAL.

Questionable CAS 110-41-8 / PERFUMING

Methylundecanal is an aromatic aldehyde primarily utilized in cosmetic and skincare formulations for its distinct citrus, aldehydic, and ambergris-like scent profile. It functions exclusively as a perfuming agent, imparting an olfactive characteristic rather than offering direct dermatological benefits.

Fragrance

Science

Methylundecanal interacts with olfactory receptors to create a sensory experience. In topical applications, its role is confined to contributing a specific fragrance. The available data does not indicate any direct mechanism of action that confers therapeutic benefits to the skin.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

Methylundecanal serves exclusively as a fragrance component; therefore, 'dusting' related to therapeutic efficacy thresholds is not applicable to its use.


The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

This ingredient is soluble in various oils (fixed oils, paraffin oil), alcohols (ethanol, propylene glycol, dipropylene glycol), glycols, silicones, and DMSO. It demonstrates limited solubility in water and glycerin. For optimal formulation, Methylundecanal should be incorporated into the oil phase, with processing temperatures kept below 60°C. It exhibits robust stability across a wide range of product types including alkalis, amines, ammonia, antiperspirants, creams, and shampoos.


Safety

CIR Status
Not reviewed
Max tested
2%
Sensitization risk Moderate

Methylundecanal is Generally Recognized as Safe (GRAS) by the FDA when used as a flavoring agent in food. Safety assessments by the Research Institute for Fragrance Materials (RIFM) indicate a favorable Margin of Exposure (>100) for repeated dose and reproductive toxicity, and a No Expected Sensitization Induction Level (NESIL) of 2900 μg/cm² for skin sensitization. However, the European Chemicals Agency (ECHA) GHS classification notes that it can cause skin irritation (H315) and may cause an allergic skin reaction (H317). The European Commission's Scientific Committee on Consumer Safety (SCCS) has highlighted a lack of human contact allergy data for this substance.


Your Skin

No Normal
No Dry
No Oily
Yes Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Questionable

While often used for its appealing scent, Methylundecanal offers no skin benefits and carries a moderate risk of skin irritation and allergic reaction, making its inclusion in precision skincare formulations questionable.


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