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METHYLCYCLOPENTENOLONE.

Avoid CAS 80-71-7 / PERFUMING

Methylcyclopentenolone is a synthetic compound primarily valued for its sweet, caramel-like scent, making it a common fragrance and flavoring agent. While utilized in various cosmetic formulations for its aroma, no specific therapeutic or beneficial mechanisms of action for the skin have been identified.

Fragrance Ingredient

Science

This ingredient functions solely as an aroma chemical, imparting a distinct scent to formulations. There is no identified mechanism of action by which Methylcyclopentenolone provides therapeutic or cosmetic benefits to the skin.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

Methylcyclopentenolone is primarily a fragrance ingredient without identified active precision skincare benefits. It is not typically 'dusted' by misrepresenting minor effects, but its inclusion for reasons other than scent in a precision formulation would lack scientific justification.


The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

The compound exhibits stability under normal ambient temperatures. It should be incorporated into formulations during the final processing stage, with temperatures maintained below 40°C. Optimal storage conditions include a tightly sealed container, protected from both light and heat.


Safety

CIR Status
Not reviewed
Sensitization risk High

Methylcyclopentenolone is classified as a Skin Sensitizer Category 1 and Serious Eye Damage Category 1. While human skin irritation tests at 3% and rabbit tests at 100% indicated no irritation, severe eye irritation was observed with undiluted material in an in vitro assay. Skin sensitization data is conflicting; a human maximization test at 3% and an in vitro LuSens assay showed no evidence of sensitization, yet it was active in a DPRA in chemico analysis. It also holds an Acute Oral Toxicity Category 4 classification. The Cosmetic Ingredient Review (CIR) has not assessed this ingredient.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Avoid

Methylcyclopentenolone offers no identified skin benefits, and its classification as a Skin Sensitizer Category 1 and Serious Eye Damage Category 1, combined with unreviewed CIR status, deems it unsuitable for precision skincare formulations.


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References