Science
Mechanism of Action
There is no identified specific mechanism of action on the skin that would provide therapeutic or cosmetic benefits. Its function in cosmetic products is predominantly as a perfuming agent, contributing to the scent profile.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
This compound generally maintains its structural integrity under standard temperature and pressure conditions. For optimal stability, it should be stored in a tightly sealed container, in a cool, dry environment, and protected from light exposure.
Conflicts
- incompatible materials (general warning)
Safety
Safety Profile
Methyl 2-Thio 3-Methyl Pyrazine (CAS 67952-65-2) has been documented to cause serious eye and skin irritation, alongside potential respiratory irritation. Recommended precautionary measures include avoiding inhalation of dust/fume/gas/mist/vapors/spray and thorough washing after handling. It is listed as FEMA GRAS (Generally Recognized As Safe) for flavoring purposes (FEMA 3208). However, it's worth noting that the FDA may no longer support the use of certain synthetic flavoring substances, which could potentially extend to related pyrazines. A RIFM safety assessment for the related compound, 2-ethyl-3-methylpyrazine, indicated no concerns for skin sensitization at current usage levels and no photoirritation, though this assessment is for a distinct chemical entity.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Methyl-methylthiopyrazine is not recommended for precision skincare formulations due to a complete lack of identified skin benefits and a high documented risk of skin irritation.
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