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METHYL ISOVALERATE.

Questionable CAS 556-24-1 / PERFUMING

Methyl Isovalerate is an ester primarily utilized in cosmetic formulations for its distinct fruity aroma, often described as apple, pineapple, or sweet. While generally considered to have low acute toxicity, direct contact can induce skin and eye irritation, necessitating careful handling and formulation.

perfuming

Science

Methyl Isovalerate functions as a perfuming agent, imparting a characteristic fruity, apple-like, or sweet scent to skincare and cosmetic formulations. It does not contribute any direct active benefits to skin physiology.


Research

Insufficient-data confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

Methyl Isovalerate is a fragrance ingredient and is not typically 'dusted' in the context of active ingredients.


The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

As an ester, Methyl Isovalerate is susceptible to hydrolysis, reacting exothermically with strong acids or strong bases. It demonstrates instability and incompatibility with strong oxidizing agents, elevated temperatures, direct sunlight, and sources of ignition.

Conflicts

  • strong acids
  • strong bases
  • strong oxidizing agents
  • heat sources
  • direct sunlight

Safety

CIR Status
Not reviewed
Sensitization risk Moderate

Methyl Isovalerate is recognized by the FDA as a Generally Recognized As Safe (GRAS) flavoring agent for food use (21 eCFR 172.515). Despite its generally low toxicity profile, improper handling can lead to irritation of the skin, eyes, and respiratory system. Strict adherence to proper handling, storage, and the use of personal protective equipment are essential to mitigate exposure risks.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Questionable

Methyl Isovalerate is primarily a fragrance component whose use in precision skincare is questionable due to its unreviewed safety status by CIR and documented potential for moderate skin irritation.


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