Science
Mechanism of Action
No specific mechanism of action on the skin has been identified or described for Methyl Ethylacetoacetate in the available research. Its primary utility is confined to its olfactory properties.
Research
Clinical Evidence
Insufficient-data confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Methyl Ethylacetoacetate is soluble in alcohol. Although some reports indicate insolubility in water, an estimated water solubility of 5.276e+004 mg/L (52.76 g/L) at 25 °C suggests significant aqueous dispersibility. For optimal stability in formulations, maintaining a neutral pH range is advisable, as related acetoacetate compounds exhibit instability in the presence of strong aqueous acids or bases.
Conflicts
- Strong aqueous acids
- Strong aqueous bases
- Oxidizing materials
Safety
Safety Profile
Methyl Ethylacetoacetate (CAS 51756-08-2) has not undergone specific safety assessments by the Cosmetic Ingredient Review (CIR) or the Scientific Committee on Consumer Safety (SCCS) for cosmetic use. However, related compounds, Methyl acetoacetate (CAS 105-45-3) and Ethyl acetoacetate (CAS 141-97-9), are approved by the FDA as food flavoring agents. These related substances demonstrate low animal toxicity, with Ethyl acetoacetate reporting an oral LD50 of 3.98 g/kg in rats and generally noted to be less irritating to skin and eyes than its methyl ester counterpart.
Your Skin
Skin Compatibility
Our Assessment
Verdict
With its primary identified role as a fragrance agent and a lack of specific cosmetic safety assessments or demonstrated skin benefits, further data is required to determine its value in precision skincare.
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