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METHYL DIETHANOLAMINE.

Valuable CAS 105-59-9 / FILM FORMING

Methyl Diethanolamine (MDEA) is a water-soluble alkanolamine primarily functioning as a pH regulator and neutralizing agent in cosmetic formulations. It enhances product stability by mitigating pH drift and aids in the uniform dispersion of pigments. While not a direct skin active, its role is crucial for optimizing the performance and longevity of other ingredients.

Summary

Neutralizing Agent pH Regulator Emulsifier Conditioner Surfactant

Science

Mechanism of Action

Methyl Diethanolamine operates as a neutralizing agent within cosmetic formulations, adjusting and maintaining the pH within an optimal range. This regulation minimizes pH drift, thereby preserving the stability and efficacy of sensitive ingredients. Its action also supports increased resin solubility and facilitates the homogenous dispersion of pigments throughout a product.

Research

Clinical Evidence

Insufficient-data confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Methyl Diethanolamine exhibits robust stability under normal conditions, resisting both thermal and chemical degradation. It functions as a pH regulator to improve overall solution stability by reducing pH drift. Its conjugate acid has a pKa of 8.52, indicating its buffering capabilities.

Conflicts

  • Strong oxidizing agents
  • Acids
  • Isocyanates
  • Halogenated organics
  • Peroxides
  • Phenols (acidic)
  • Epoxides
  • Anhydrides
  • Acid halides
  • Strong reducing agents (e.g., hydrides, can generate flammable hydrogen)
  • Air contact
  • Direct sunlight
  • Heat
  • High temperature

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Methyl Diethanolamine is generally considered a low-hazard material, with low anticipated risk of adverse health effects from consumer use, particularly at low concentrations in cosmetic products. While it has been reported to cause slight skin irritation and moderate to serious eye irritation, animal studies indicate no skin irritation (rabbit) and non-sensitizing properties (guinea pig). It is listed in the FDA Inventory of Food Contact Substances (FCS).

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Methyl Diethanolamine is a valuable formulation ingredient, critical for maintaining product stability, optimizing pH, and supporting the effective dispersion of components, thereby indirectly enhancing the performance of skincare formulations.

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